Other names: Holly bay, beaver tree, indian bark, red laurel, swamp laurel, sweet magnolia, sassafras
Scientific name: Magnolia glauca, magnolia grandiflora
Arabic names: المغنولية (al maghnooliah)
Rain Forest names:
Approximate number of species known:
Common parts used: bark
The magnolia tree is known for the beauty and fragrance of its flowers.
The bark has been used for its quinine content.1 It has been used to help people give up tobaccao addiction.1 It has been used for fever.1 Externally it has been used on the skin1.
Generally considered that it can be taken for a long time with no ill effects.1 In the modern day it is considered contra indicated with MOI (Monoamine Oxidase Inhibitors) antidepressants.
The effect of magnolia bark extract (MBE) on different variables related to caries and gingivitis administered daily through a sugar-free chewing gum was evaluated.
The study was performed with healthy adult volunteers at high risk for caries as a randomized double-blind interventional study. 120 subjects with a salivary mutans streptococci (MS) concentration ≥10(5) CFU/ml and presence of bleeding on probing >25% were enrolled and divided into three groups: magnolia, xylitol and control.
The study design included examinations at baseline, after 7 days, after 30 days of gum use and 7 days after the end of gum use. Plaque pH was assessed using the strip method following a sucrose challenge.
Area under the curve (AUC(5.7) and AUC(6.2)) was recorded. Whole saliva was collected and the number of salivary MS (CFU/ml) was counted. Bleeding on probing was recorded as a proxy of dental plaque. Data were analyzed using ANOVA repeated measures.
Magnolia gum significantly reduced plaque acidogenicity, MS salivary concentration and gingival bleeding compared to xylitol and control gums.
Thirty-day use of a chewing gum containing MBE showed beneficial effects on oral health, including reduction of salivary MS, plaque acidogenicity and bleeding on probing.
Affective and behavioural disorders possibly concomitant to the vasomotor menopausal symptoms worsen quality of life. A rational formulation containing soy isoflavones (60 mg), lactobacilli (500 millions spores), calcium (141 mg) and vitamin D3 (5 microg) was added of Magnolia bark extract (60 mg) and magnesium (50 mg) (Estromineral serena, ES).
The Magnolia extract active principles interact with GABA system and exhibit a sedative central action. Magnesium intervenes in enzymatic reactions of the energetic metabolism and protects the bone integrity.
A controlled, randomised, multicentre study was carried out in symptomatic menopausal women with sleep or mood alterations. Women received 1 tablet/day of ES or Ca+D for 24 weeks. Symptoms during the treatment and final judgements on efficacy and acceptability were evaluated.
Eighty-nine women participated to the study. Flushing, nocturnal sweating, palpitations, insomnia, asthenia, anxiety, mood depression, irritability, vaginal dryness, dyspareunia, and libido loss, significantly decreased in severity and frequency during ES versus Ca+D treatment even since the fourth week.
Woman wellbeing (good/very good 66.7% vs 20%) judgement on efficacy (72.7% vs 17.1%) and acceptability (93.9% vs 31.4%) were significantly better for ES.
The controlled study showed the efficacy of Magnolia extract and magnesium on psycho-affective and sleep disturbances in menopause, in addition to the effects of isoflavones on vasomotor symptoms. A global natural approach to menopause with ES evidenced its therapeutic usefulness and safety.
Campus G, Cagetti MG, Cocco F, Sale S, Sacco G, Strohmenger L, Lingstrom P. “Effect Of Sugar-Free Chewing Gum Containing Magnolia Bark On Different Variables Related To Caries And Gingivitis: A Randomized, Controlled Intervention Trial.” 2011 http://www.ncbi.nlm.nih.gov/pubmed/21822018
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, Volpini G, Benvenuti C. “Soy Isoflavones, Lactobacilli, Magnolia Bark Extract, Vitamin D3 And Calcium. Controlled Clinical Study In Menopause.” 2006 August http://www.ncbi.nlm.nih.gov/pubmed/16957676